Honey collection is an ancient activity. Humans apparently began hunting for honey at least 10,000 years ago, as evidenced by a cave painting in Valencia, Spain. The painting is a Mesolithic rock painting, showing two female honey-hunters collecting honey and honeycomb from a wild bee nest. The two women are depicted in the nude, carrying baskets, and using a long, wobbly ladder to reach the wild nest. Historically, honey has been used by humans to treat a variety of ailments through topical application, but only recently have the antiseptic and antibacterial properties of honey been chemically explained.